This article explores the evolution of machine tools showcased at JIMTOF 2022, focusing on Process Integration and Factory Automation to address labor shortages and decarbonization. Key highlights include in-machine measurement, 5-axis multitasking, and the integration of special processes (e.g., AM and FSW) to achieve "Done-in-One" efficiency. Furthermore, advancements in AI vision, collaborative robots, and AMRs overcome obstacles in long-term unmanned operations. The article concludes that the synergy between hardware, software, and Digital Twin technology is the vital driver for the industry’s Digital and Green Transformation (DX/GX).